How It Works: The Science of C&P FLAMESHIELD
 
Inflammation is a natural bodily response, but when left unchecked, it may contribute to discomfort and stiffness, potentially affecting mobility and overall wellbeing.
The body's inflammatory processes are complex, involving multiple pathways that, when overactive, can lead to oxidative stress and tissue irritation. C&P FLAMESHIELD combines clinically studied ingredients to help support the body's natural inflammatory response mechanisms.
 
1) Curcumin – Targeted Inflammatory Response Support
285mg of Curcumin, the active compound in turmeric, has been shown in clinical studies to help modulate key inflammatory markers. Its antioxidant properties may also support cellular protection against oxidative stress.
 
2) Boswellia – Joint Comfort & Mobility Support
300mg of Boswellia serrata extract contains active compounds called boswellic acids, which research suggests may help maintain joint flexibility and comfort by influencing inflammatory enzymes.
 
3) Quercetin – Cellular Protection & Immune Modulation
100mg of Quercetin, a potent flavonoid, has demonstrated antioxidant properties and may support healthy immune system responses to inflammation.
 
4) Ginger Extract – Complementary Support
20mg of Ginger extract works synergistically with other ingredients, with studies indicating potential benefits for managing inflammatory responses.
 
5) Piperine – Enhanced Bioavailability
5mg of Piperine from black pepper has been shown to increase the absorption of curcumin by up to 2000%, ensuring optimal delivery of active compounds.
 
C&P FLAMESHIELD May Support:
✔ Healthy inflammatory response mechanisms*
✔ Joint comfort and mobility*
✔ Antioxidant protection against oxidative stress*
✔ Immune system balance*
 
At C&P, we formulate our products based on the latest scientific research, using high-quality ingredients in precise dosages. FLAMESHIELD represents our commitment to evidence-based nutritional support.
 
Clinical Mechanisms & Research
Each ingredient in C&P FLAMESHIELD has been carefully selected based on clinical research demonstrating its role in modulating inflammation, supporting joint health, and enhancing antioxidant defences. Below is a breakdown of the mechanisms of action and supporting studies for each component.
 
1. Curcumin (285mg) – The Gold Standard for Inflammation Support
Mechanisms of Action:
NF-κB Inhibition: Curcumin suppresses NF-κB, a master regulator of inflammation, reducing pro-inflammatory cytokines (TNF-α, IL-6, IL-1β).
COX-2 & LOX Inhibition: Unlike NSAIDs (which only block COX-2), curcumin also inhibits 5-LOX, providing broader anti-inflammatory effects.
Antioxidant Boost: Increases glutathione (GSH), superoxide dismutase (SOD), and catalase levels, protecting cells from oxidative damage.
Key Clinical Evidence:
Meta-Analysis (2021) – 1,000mg/day curcumin significantly improved joint pain and mobility in osteoarthritis patients (J Med Food).
RCT (2019) – Curcumin was as effective as ibuprofen for knee osteoarthritis pain, without GI side effects (J Altern Complement Med).
 
2. Boswellia serrata (300mg) – Protects Joints & Cartilage
Mechanisms of Action:
5-LOX Inhibition: Boswellic acids block leukotriene synthesis, reducing inflammation in joints.
MMP Inhibition: Prevents cartilage breakdown by inhibiting matrix metalloproteinases (MMPs).
Key Clinical Evidence:
RCT (2020) – 300mg/day Boswellia improved knee pain and mobility in osteoarthritis (Phytother Res).
Study (2019) – Boswellia reduced CRP (C-reactive protein), a key inflammation marker (J Inflamm Res).
 
3. Quercetin (100mg) – Potent Antioxidant & Immune Modulator
Mechanisms of Action:
Nrf2 Activation: Boosts production of glutathione and SOD, enhancing cellular antioxidant defences.
Mast Cell Stabilisation: Reduces histamine release, helping balance immune responses.
Key Clinical Evidence:
Study (2020) – Quercetin lowered IL-6 and TNF-α in athletes, reducing post-exercise inflammation (Nutrients).
Meta-Analysis (2018) – Quercetin supplementation improved endothelial function, supporting circulation (J Am Heart Assoc).
 
4. Ginger Extract (20mg) – Natural COX-2 Inhibitor
Mechanisms of Action:
COX-2 Suppression: Gingerols inhibit prostaglandin synthesis, similar to NSAIDs but without side effects.
Antioxidant Effects: Scavenges ROS (reactive oxygen species) and reduces oxidative stress.
Key Clinical Evidence:
RCT (2015) – 500mg ginger/day reduced muscle pain by 25% post-exercise (J Pain).
Meta-Analysis (2020) – Ginger improved osteoarthritis pain comparably to NSAIDs (Arthritis).
 
5. Piperine (5mg) – Enhances Bioavailability by 2000%
Mechanisms of Action:
Inhibits Drug Metabolism Enzymes: Blocks CYP3A4 & P-glycoprotein, slowing curcumin breakdown.
Increases Gut Absorption: Enhances intestinal permeability for better nutrient uptake.
Key Clinical Evidence:
Landmark Study (1998) – Piperine increased curcumin absorption by 20x (Planta Med).
Follow-up Study (2021) – Confirmed piperine’s role in boosting bioactive compound absorption (Phytother Res).
 
These statements are based on scientific research into the individual ingredients. This product is not intended to diagnose, treat, cure or prevent any disease. Food supplements should not replace a varied diet and healthy lifestyle.